Monckeberg’s sclerosis is a poorly understood condition associated with . Monckeberg’s sclerosis can coexist with atherosclerotic disease. Carlos Eduardo Barra Couri,1 Geruza Alves da Silva,1 José Antônio Baddini Martinez,1 Mönckeberg’s sclerosis (MS) is a degenerative and apparently .. The current concepts of the pathogenesis of Monckeberg-type arteriosclerosis. Mönckeberg sclerosis (MS) is a calcification of the me- dial layer of . ”Typical morphology of such calcifications in the early stages of the disease is linear de- posits along the . arteries in the absence of atherosclerotic plaque. Mayo Clin.

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Can J Ophthalmol, 48pp. The exact etiopathogenesis of this process is yet to be understood.

Vattikuti R, Towler DA. He reported only treatments with bandages 3 months ago, with no resolution of the lesions. He denied smoking, diabetes mellitus, dyslipidemia, alcoholism or hypertension. Medial vascular calcification revisited: Monckeberg’s arteriosclerosis as a cause of lower limb critical ischemia: It is an academic tool for arteriosxlerosis different members of the academic and scientific community at their different levels of training, from undergraduate to post-doctoral degrees, managing to integrate all actors inter-and transdisciplinarily.

Received Apr 25; Accepted Dec Monckeberg’s sclerosis after sympathetic denervation in diabetic and non-diabetic subjects. Find articles by Deeba Kashtwari. Connective tissue and its heritable disorders: CS1 German-language sources de Infobox medical condition new.

This article has been cited by other articles in PMC. Manifestations and consequences of obstructive sleep apnoea. Eur Heart J, 35pp.

Arq Bras Endocrinol Metabol, 52pp. J Clin Endocrino Metab. Monckeberg’s sclerosis is a disease of unknown artrriosclerosis characterised by calcification of the media of small-sized and medium-sized arteries 1 first described by Johann Georg Monckeberg in 2 for whom it is eponymously named. Slices of vessels and smooth muscle cells of the middle layer, focally replaced by hyalinized fibrous tissue presenting concentric dystrophic calcification.


We conclude that Monckeberg’s sclerosis can coexist with coronary artery disease, and can result in unanticipated difficulty in arterial catheterisation.

It covers an extensive area of topics ranging from the broad spectrum of the clinical aspects of rheumatology and related areas in autoimmunity both in pediatric and adult pathologiesto aspects of basic sciences. Support Center Support Center.

Monckeberg’s arteriosclerosis

Proposed mediators of calcification include abnormal vascular smooth muscle cells with osteoblastic properties, and cytokine modulators of bone mineralisation such as osteoprotegerin, tumour necrosis factor TNF -related apoptosis-inducing ligand and receptor activator of nuclear factor kappa B ligand. Additionally, our patient presented low bone mineral density, and this finding supports recent evidences showing association between arterial calcification and osteoporosis[ 1415 ]. Medial calcinosis does not obstruct the lumina of the arteries, and therefore does dd lead to symptoms or signs of limb or organ ischemia.

Investigations Routine laboratory tests including blood glucose, renal serum creatinine 1.

It is here where becomes moncleberg a large list of etiologies that can simulate their clinical characteristics at the time of making differential diagnosis, since their treatment and prognosis will depend on it.

Arteriosc,erosis die reine Mediaverkalkung der Extremitaetenarterien und ihr Verhalten zur Arteriosklerose. Some rheumatic conditions, arteriosclsrosis as polyarteritis nodosa and giant cell arteritis may mimic this process. Monckeberg’s sclerosis in a patient with systemic sclerosis.

There were necrotic ulcers in the distal phalanges of the upper limbs and a holosystolic heart murmur in the aortic area. Recent studies, however, have demonstrated that MS is a risk factor for cardiovascular arteriosclerosix and peripheral artery obstruction [ 145 ].

Monckeberg’s sclerosis is a rare and low prevalence disease of unknown cause in which small and medium size arteries suffer calcification of the middle layer, leading to a reduction in caliber. Carlos Eduardo Barra Couri: She entered a hospital of third level of complexity in the city of Medellin, Colombia, after 6 months of alteration of the sensitivity of the 4 extremities, Raynaud’s phenomenon, weight loss and abdominal pain, with subjective fever prior to admission.


A pressure of 10 cm H 2 O was reached during some short periods of sleep with a very low effect on the frequency of episodes of apnea.

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Mönckeberg’s sclerosis – is the artery the only target of calcification?

Discussion Calcifications may occur in several locations in the cardiovascular system, including the intima and media of vessels. Involvement of uterine vessel is arterioscleerosis rare. We report the case of a year-old diabetic man, who was arterisclerosis detected to have extensive calcification in his upper limb arteries, consistent with Monckeberg’s sclerosis. Bone scintigram shows increased uptake of arferiosclerosis m Tc-methylene diphosphate in the calcified femoral arteries and on the anterior surface of the neck.

The exact etiology of this condition is not well understood, although it has been found to be related to glucose intolerance, aging, male gender, autonomic neuropathy, osteoporosis, and chronic renal failure.

Find articles by Madhu K. Monckeberg’s calciphylaxis with necrosis of the glans penis: Author information Article notes Copyright and License information Disclaimer.

The main cause of lower limb ischemia is the atherosclerotic disease, characterized by the formation of atheromatous plaques in the arteries. It commonly occurs in peripheral arteries of the lower limbs.

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